Trenbolone acts like selective androgen receptor modulators

Trenbolone is an anabolic steroid that is taken by bodybuilders for many years. Unfortunately, this medicine has never been claimed to be an excellent preparation for clinical needs. It isn’t approved for human use by the U. S. Food and Drug Administration (FDA). This medicine has been demonized many times by media. A lot of articles have reported that this medicine is quite dangerous. But recent researches have shown opposite aspects. It is believed that general attitude to this medicine can be soon changed. Experts from Florida, including Joshua Yarrow, claim that this product can be used as testosterone for hormone replacement therapy. They are sure that it is an effective alternative preparation to testosterone for the purpose mentioned above. Results of researches conducted by these specialists have been published in the American Journal of Physiology – Endocrinology and Metabolism.
Moreover, the specialists assure that trenbolone enanthate has even certain priorities over testosterone for several patients. Bodybuilders know and support the statements connected with this medicine. As it is known, testosterone aromatases. As for trenbolone, it is converted neither to estradiol, nor to dihydrotestosterone (DHT). That’s why trenbolone doesn’t cause unwanted effects related to estrogen and DHT.
Joshua Yarrow reports about the researches conducted by him and his colleagues. Castrated rats have been given trenbolone enanthate. Even low quantities of this product have induced their muscle size and kept bone mineral density. There have not been observed such undesirable symptoms, as enlargement of prostate or polycythemia in these lab rats.
But extremely increased dosages of testosterone enanthate were required to cause the same anabolic effects in muscles as were produced by low dosages of trenbolone enanthate. But such undesirable symptoms, as prostate enlargement and enhanced hemoglobin accompanied the enhanced quantities of testosterone enanthate. It is suggested by the researchers that trenbolone acts like selective androgen receptor modulators, causing anabolic effects in muscles and bones without androgenic unexpected results.
Professional competitive bodybuilders prefer administrating trenbolone several weeks before competitions because it lead to fat loss. Moreover, the researches have displayed that the same quantities of trenbolone have stronger lipolytic effects than those of testosterone. It has been determined that more trenbolone a person administrates, the greater the fat loss is caused.
Since trenbolone lacks aromatization, it is commonly taken together with such steroids, as testosterone, Dianabol or with another aromatizable steroid. The lack of aromatization makes trenbolone unable to be used alone for testosterone replacement therapy. The non-aromatizable feature of this steroid is responsible for just partial protection of bones.
Nevertheless, it is possible to conclude that additional researches are needed in order to apply trenbolone for hormone replacement therapy.